This is a preview. Log in through your library . Abstract Arp2/3 complex nucleates branched actin filaments that provide pushing forces to drive cellular processes such as lamellipodial protrusion and ...

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...

Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing ...

Model showing the release of phosphate in different parts of the actin filament. Actin in the core of the filament has a closed door while the back door at the end of the filament is open. A mutation ...

Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing ...

Actin filaments are dynamic protein-fibers in the cell built from single actin proteins. Many cellular functions, including cell movement, are regulated by constant filament assembly and disassembly.

“We are answering fundamental questions of life that scientists have been trying to answer for several decades”, remarks Raunser. In eukaryotic cells, actin proteins are abundant and tend to join ...

Research has demonstrated that actin waves propagate via actin polymerization on the substrate-attached cell membrane at the wave’s front and disassembly at the back of the wave. 4 Proteins named Arp2 ...

Actin proteins assemble into thin, helical filaments that form a network throughout all eukaryotic cells. These filaments play a significant role in cell structure, movement, division, and more. This ...

In all eukaryotic cells, actin protein assembles to form a network of thin filaments that spread throughout the cell. The actin filaments give the cell its structure, enable the cell to move, and ...