The awe-inspiring process of cell division can turn a fertilized egg into a baby – or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process ...

The induction of the cell cycle in cardiomyocytes involves the activation of specific genes that are responsible for regulating cell division and growth. Our laboratory has discovered several ...

Many cancer-driving mutations disable a key checkpoint in the cell’s cycle between growth and division, resulting in unchecked activity of the E2F family of transcription factor proteins. A set of ...

Inside the human airway, a certain cell type reigns supreme: multiciliated cells, decorated with dozens of hair-like cilia all beating in tandem. These cells are responsible for clearing out foreign ...