For roughly 30 years, biology students have learned the same tidy diagram of the inside of the nose: four broad zones, each ...
G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a ...
Adhesion G protein-coupled receptors have a large extracellular region (shown in green and orange) that extends into space outside the cell. Almost 35% of drugs approved by the Food and Drug ...
A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled receptors in living cells actually respond to activating substances. The ...
Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...
Researchers from the University of Birmingham have uncovered a completely new mechanism by which fat cells (adipocytes) control how they store and release fat. The results of the study change our ...
A team of researchers has successfully created more effective immune cells that can fight cancer without damaging healthy tissue. "This story goes back nearly 20 years," says Prof. Paul François. This ...
Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...
Details and references regarding individual diseases are provided in the Supplementary Appendix. CIDP denotes chronic inflammatory demyelinating polyneuropathy, Covid-19 coronavirus disease 2019, and ...