Inflammation is a local, protective response to microbial invasion or injury. It must be fine-tuned and regulated precisely, because deficiencies or excesses of the inflammatory response cause ...

Key components of the non-neuronal cholinergic system (NNCS) including nAChRα7 are strongly expressed in macrophages. The NNCS regulates phagocytosis in macrophages via multiple signaling pathways ...

Three the approved drugs for Alzheimer’s disease attempt to boost the brain’s supply of acetylcholine, a critical neurotransmitter for cognition that wanes in people with the disease. But might ...

August 16, 2010 — Significant differences in central cholinergic functioning have been identified between cocaine-addicted patients and healthy control patients in regions of the brain that are highly ...

Best known for its role in colorectal cancer, the protein adenomatous polyposis coli (APC) has recently been found to play an essential role in the nervous system. This new study provides novel ...