Diagnostic algorithms for axial spondyloarthritis (SpA), and classification criteria for use in clinical trials, are being developed and refined. But can axial SpA be ruled out in young patients with ...

There is no specific “diagnostic” or pathognomonic laboratory marker for ankylosing spondylitis/axial spondyloarthritis (AS/axSpA), and diagnosis is based on clinical history, physical examination and ...

Axial disease is common and burdensome in patients with psoriatic arthritis (PsA). Human leukocyte antigen-B27 (HLA-B27) is a risk factor for axial PsA; treatment response by HLA-B27 status is ...

The HLA-B27 genetic marker is known to be associated with increased risk for various arthropathies, including JIA. Whether the genetic marker's presence has prognostic value has been uncertain. In ...

Human leukocyte antigen (HLA) typing is important in organ transplantation protocols, as they determine the likelihood of rejection. The HLA system is little understood, however. In simple terms, the ...