Twenty-two years after the completion of the Human Genome Project, scientists have unveiled the most expansive catalog of human genetic variation ever compiled. Across two new papers published ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

You can always be judged by your scars. This is the idea that sums up what researchers at Spanish National Cancer Research Centre (CNIO) claim is one of the new breakthroughs in basic and biomedical ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Researchers have used a new human reference genome, which includes many duplicated and repeat sequences left out of the original human genome draft, to identify genes that make the human brain ...

Ancient DNA is turning human evolution into a crime scene reconstruction, and one of the prime suspects is a herpesvirus that ...

James Watson was credited as the co-discoverer of the structure of DNA. Watson was a Nobel laureate and the former Chancellor of Cold Spring Harbor Laboratory. Photograph by Max S. Gerber, Redux James ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

When Neandertals were first discovered nearly 170 years ago, the conceptual gap between their lineage and that of modern humans seemed vast. Initially scientists prejudicially believed that the ...