Lymph nodes, hundreds of small structures located throughout the body, play a pivotal role in immunity, including anti-tumor immune responses. White blood cells, also known as lymphocytes, reside in ...

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells. But new findings from a clinical trial show that immunotherapy can activate ...

New research shows lymph nodes aren’t just cancer bystanders, they’re the command centers fueling immune attacks. Surgically removing them along with tumors may weaken treatment, while preserving them ...

Scientists with the Fralin Biomedical Research Institute at VTC have created an engineered model of the supportive tissue found within a lymph node to study human health. Working with scientists at ...

A picture of immune cells in a lymph node. Resident cells are marked in red, circulating ones in cyan. What is striking is that regulatory T cells (outlined in yellow) are found in both forms. The ...

Stanford University-led researchers report that tumor cells hijack mitochondria from immune cells, reducing anti-tumor immune function and activating cGAS-STING and type I interferon signaling that ...