Macrophages patrol the body's tissues for potential threats such as invading microbes or cancerous cells. Macrophages can engulf and kill these threats, as well as send signals to other immune cells ...

NETs promote macrophage expression of T-cell chemokines and subsequently facilitate cytotoxic CD8+ T cell infiltration and granzyme B production, which drives kidney fibrosis in obstructive ...

Our new findings suggest that these changes in macrophages are actually readily reversible and do not inherently encode immune memory. Instead, the cells are dependent on ongoing signaling from ...

Multiple sclerosis (MS) is a chronic neurological disease characterized by nerve damage and consequent impairments in vision, movement, balance and mental function. In MS, the immune system mistakenly ...

Angus Chen covers all issues broadly related to cancer including drugs, policy, science, and equity. He joined STAT in 2021 after covering health and science at NPR and NPR affiliate stations. His ...

Macrophages are some of the body’s most potent weapons against invading cellular threats. Like immunological ‘Hungry Hungry Hippos,’ macrophages engulf and dispose of cancer cells or invasive ...

We have identified a macrophage population "Mrep" that plays an essential role in muscle repair. However, in Fibrodysplasia ...

Intermediate-scale benchtop bioreactor protocol streamlines production of iPSC-derived macrophages for research, drug discovery, and modeling.

Melanoma cells with the cell membrane protein CD44 stained in red and the nucleus in blue. Dil-labelled extracellular vesicles taken up by cancer cells are shown in green. Image by Kaisa Mäki-Mantila.

When cancer cells begin to die within tumors, they expose signals on their surface that indicate they are dying. Macrophages then detect these signals and engage in phagocytosis, where they eat the ...