LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

Every year, more than 100 million animals are used globally in biomedical research, yet over 90% of drugs that appear effective in animal trials fail during human clinical testing. 1 This staggering ...

A figure from the research paper shows that both the model and experimental animals learned a task at a very similar pace. A new computational model of the brain based closely on its biology and ...

In this whitepaper, Sartorius discusses the need to replace animal testing with advanced in vitro human cell models for pharmaceutical, chemical, and cosmetic development as, with only 5-10% of ...

Representative immunofluorescence images showing the intestinal epithelium of a murine colitis model treated with either PBS or glycyrrhizin, adapted from Figure 2F. Cleaved Caspace-3 (red), EpCAM ...

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development - including the ...