Researchers developed the novel and publicly available computational tool Millefy to visualize heterogeneity in RNA biology between single cells. Using mouse embryonic stem cells and cells from triple ...

RNA molecules play critical roles in regulating gene expression. Perturbation of RNA processing and metabolism underlies a wide range of human diseases. RNA research in the Department of Genetics and ...

There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the right times. RNA is one such molecule; the sequences for different proteins ...

An interdisciplinary research team from two working groups at the Center for Synthetic Biology at TU Darmstadt has developed ...

Synthetic biology strives to achieve robust control of biological processes in order to create designer organisms for a variety of industrial, diagnostic, and therapeutic applications. Researchers ...

To understand more fully the role of RNA and its modifications in living systems, researchers will need robust, reproducible, and accessible tools and techniques capable of identifying all RNA ...

Researchers have visualized how a large RNA molecule assembles itself into a functional machine. RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like ...

I get frustrated every time I grab a glove and realize it’s for the opposite hand. But to synthetic biologists, this annoyance is a biological quirk that could help transform medicine. Think ...

Developing tools for precise control of biological processes has been one of the main pillars of the now mature field of synthetic biology. These scientific tools borrow principles from a multitude of ...

In recent decades, significant advances in science and technology have greatly enhanced understanding of the many biological molecules that contribute to life’s complexity. RNA is one such molecule ...