When the drug fomivirsen was approved by the FDA in 1998 for the treatment of cytomegalovirus retinitis in patients with HIV/AIDs, it was hailed as a milestone in drug discovery because it was the ...

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins – yet it exists in large quantities. A research team from ...

Courtesy of Antisense Therapeutics Ltd. Antisense strategies use polymeric nucleic acids or nucleic acid analogs to bind to and silence specific messenger RNAs. The silencing can be caused either by ...

Thank you for your article on antisense 1 and for letting us know that the subject is very much alive. Although antisense is an "RNA therapeutic" in that the target is mRNA, actually in almost all ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 50 (December 13, 2022), pp. 1-12 (12 pages) R-loops, or RNA:DNA hybrids, can induce DNA damage, which ...

According to SNS Insider's forecast, the global Antisense and RNAi Therapeutics market will grow from USD 4.15 billion in 2023 to USD 18.48 billion by 2032, at a compound annual growth rate (CAGR) of ...

DALLAS & MARTINSRIED, Germany--(BUSINESS WIRE)--Celanese Corporation (NYSE: CE), a global specialty materials and chemical company, and Secarna Pharmaceuticals GmbH & Co. KG, a leading independent ...

Patients receiving a kidney transplant and who are positive for BK virus (BKV) are at risk of losing their transplant due to BKV reactivation. At this time, there are no antiviral options available ...