After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

Copine-6 is a calcium-sensitive phospholipid-binding protein of the evolutionarily conserved Copine family. In the central nervous system, Copine-6 regulates function of some neurotransmitter ...

(A) Results of DNA microarray datasets analyzing brown adipose tissue (BAT) from adipose tissue-specific Vegfa knockout mice (Adipo- Vegfa KO) (GSE221854) or high-fat diet (HFD) fed wild-type mice ...

MCM8 deficiency impairs meiotic homologous recombination repair, but the specific role of MCM8 in mitotic germ cells remains poorly understood. This study reveals that MCM8 interacts with helicase ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

Although the Arabidopsis thaliana RPD3-type histone deacetylase HDA19 and its close homolog HDA6 participate in SIN3-type histone deacetylase complexes, they display distinct biological roles, with ...

Stabilization of microtubule plus end-directed kinesin CENP-E at the metaphase kinetochores is important for chromosome alignment, but its mechanism remains unclear. Here, we show that CKAP5, a ...

Clear-cell renal cell carcinoma (ccRCC) poses a significant challenge in cancer treatment, with high rates of resistance to radio and chemotherapy and poor patients’ outcomes at late diagnosis. The ...

Notably, one specific branch of the Metaviridae, the Errantiviruses or insect endogenous retroviruses (iERVs), stands out due to a key biological trait: infectivity (Stefanov et al, 2012; Terzian et ...

Phase-separated p62 bodies activate NRF2, a key transcription factor for antioxidant response, by sequestering KEAP1, which targets NRF2 for degradation. Although p62 bodies containing KEAP1 are ...

Arthritis was induced in mice exposed to high blood levels of homocysteine. Hyper-homocysteinemia arthritic animals develop diastolic dysfunction (the left ventricle does not dilate properly) with ...