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6:51
YouTube
Tópicos Nucleicos
CRISPR/Cas9, más allá de la edición - Parte 5
Cas9 puede ser modificada para perder su actividad de nucleasa pero manteniendo la unión del sgRNA, esto permite manipular la expresión de genes de interés sin modificar su secuencia. Referencias: https://pmc.ncbi.nlm.nih.gov/articles/PMC4937303/ https://pubmed.ncbi.nlm.nih.gov/26245833/ Video de metilación de DNA: https://www.youtube.com ...
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1 month ago
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